Grammer, famous for his comedy roles in Cheers, Frasier and even as the voice of Simpsons baddie Sideshow Bob, saw off a strong Globes field for Lead Actor in a TV drama, beating Steve Buscemi (Boardwalk Empire), Jeremy Irons (The Borgias) and Damian Lewis (Homeland”) and Bryan Cranston (for the brilliantly funny and sadly under appreciated Breaking Bad).
Boss was created by Iranian screenwriter Farhad Safinia (who co-wrote Apocalypto with Mel Gibson in 2006) and 56-year-old Grammer stars as a modern-day version of the first Mayor Daley, Richard J. Daley, the corrupt boss of the Chicago Democratic machine. The twist in the show is that Kane is trying to mask a deteriorating mental condition.
Grammer, whose recent comedy shows Back to You and Hank, were both cancelled early on, said: "I had success as a comedic actor. I thought it was time to show the audience something else. Career-wise, it's good to do things that keep people guessing. This is a big turnaround for me. Boss is a political show but really it's more about power and human behaviour. It's about a mythical major of Chicago who is diagnosed with a debilitating disease - it's really about his fight on the way down. He believes the end justifies the means."
The music for the opening credits, incidentally, is Satan, Your Kingdom Must Come Down by Robert Plant. Starz President and CEO Chris Albrecht said: "Kelsey has yet again created one of the most memorable and thrilling characters on television." Speaking after his Globes win, Grammer said: "I hope more and more people will have a chance to see it. I imagine we'll now garner quite an audience share. It's a compelling story."
Grammer admits his life has been "tabloid fodder" and it has had even more twists than a thriller. Grammer's estranged father was murdered; two half-brothers died in a diving accident; his younger sister was raped and murdered when the actor was 20; Grammer was arrested for possessing cocaine and involved in a sex-tape drama. Only two years ago, he had a heart attack and less than a year ago he split from his wife Camille, who was then cast on Real Housewives of Beverly Hills, in which she revealed salacious details of their life together.
His career is certainly on the up but so, he says, is his personal life. In 2010, he met Kayte Walsh, a former flight attendant, on a trip to London and they married in February last year. Grammer announced backstage at the Golden Globes awards that he and his wife are expecting twins - they will be Grammer's fifth and sixth children. He said: "My wife will make an extraordinary mother. She's one of the most loving, amazing, warm human beings I've ever met."
So will the new additions affect how he approaches the incredibly dark character he plays on Boss? “I’ll just be more tired actually,” he said. “It wouldn’t change the way I work. It just might change the amount of time I have.”
Grammer has always said that Frasier - which holds up still as one of the finest television comedies - has been retired for ever but playing Mayor Tom Kane might just reignite the political ambitions of a man who once said “It’s something I’ve thought about for a long time and I am open to it happening in the distant future."
In the meantime, there's a Golden Globe to celebrate and sleepless nights in store.