Aguero's recent absence has been particularly poorly timed.
Of manager Roberto Mancini's other striking options, Edin Dzeko is presently in a poor run of form, Mario Balotelli's increasing erratic behaviour is casting a shadow over the club and Carlos Tevez has not appeared fully fit since returning to the fold.
And how City's £38 million record signing ended up being sidelined has been a matter of debate since Mancini revealed a week ago that Aguero had been ruled out with a "stupid" injury.
Now, as he closes on full fitness ahead of Sunday's trip to Arsenal, Aguero has decided to set the record straight.
"During the match against Chelsea, I injured my ankle and it was sprayed with a topical anaesthetic that caused a burn on the upper part of my right foot," said Aguero.
"The injury worsened after a few days and when boils appeared I was told I wouldn't play against Stoke and then against Sunderland.
"You can imagine how I felt, being out of playing condition when my team is trying to take the championship. It's always worse from the bench.
"After that I started receiving incredible rumours about how it all happened.
"I know my life is very public and I'm willing to take criticism even if I disagree with it. but I will not sit quietly while lies are being spread - even more so if they cast doubt upon my professionalism.
"This is a simple injury and not a plot of intrigue.
"It's hard to believe it happened while we are fighting for the title," he said of his injury.
"This is the real status of my injury. I got back from practice today and it's not bothering me.
"If it all goes well, I'll be at coach's disposal next Sunday."