Visitors will be assaulted by the smell of A Thousand Years (1990), an installation in which flies emerge from maggots and feed on a rotting cow's head. They can also catch a whiff of Horror at Home (1995), consisting of a giant ashtray filled with cigarette butts.
In And Out Of Love (1991) features a room filled with live butterflies feeding on bowls of fruit. On the preview day for the show, at least one butterfly escaped by settling on a visitor's coat and accompanying them out.
Downstairs in the Turbine Hall, visitors queue to enter a pitch-dark room housing two security guards and For The Love Of God, the human skull covered in 8,601 diamonds and said to be worth £50 million.
Hirst, said to be Britain's richest living artist, defended the price of his work.
He said: "A painting probably has the most shocking increase in value, from what it costs to make to what you sell it for. But you'd never look at a Rembrandt and say, 'That's just wood and canvas and paint - how much?!'
"It’s all about how many people want it. It works on a pair of jeans as well - they're just material and stitching and as soon as you walk out of the shop, they’re worth nothing."
Asked if the gift shop skull would hold its value, he replied: "Maybe on eBay you might be all right for a bit."
:: Damien HIrst runs from 4 April - 9 September